ROLE OF TRANSPORTERS IN THE DISTRIBUTION OF PLATINUM-BASED DRUGS

ROLE OF TRANSPORTERS IN THE DISTRIBUTION OF PLATINUM-BASED DRUGS

Platinum derivatives used as chemotherapeutic drugs such as cisplatin and oxaliplatin have a potent antitumor activity.However, severe side effects such as nephro-, oto-, and neurotoxicity are associated with their use.Effects and side effects of platinum-based drugs are in part caused by their transporter-mediated uptake in target and non target c

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Study on the preferential distribution of acetyl tributyl citrate in poly(lactic) acid-poly(butylene adipate-co-terephthalate) blends

In this work, the preferential distribution of acetyl tributyl citrate plasticiser (ATBC) in poly(lactic acid) (PLA)-poly(butylene adipate-co-terephthalate) PBAT blends has been investigated.Pure plasticised PLA and PBAT blends and their binary blends (PLA/PBAT with 80 wt% of PLA and 20 wt% of PBAT and PBAT/PLA with 80 wt% of PBAT and 20 wt% of PLA

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